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humic acid 9

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hepatocellular carcinoma 4

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Mapping the structure-activity relationship of

Worawan PANPIPAT, Hasene KESKIN, Zheng GUO

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 1, Pages 105-113 doi: 10.1007/s11705-015-1502-x

Abstract: The phase behavior of twelve synthesized -sitosteryl fatty acid esters with acyl moieties with differentThe surface-pressure isotherms showed that short chain -sitosteryl fatty acid esters gave smaller meanmolecular areas and had decreased monolayer stability and the long chain steryl esters did not produceAll the steryl esters displayed strong condensing effects, but there was a pronounced structural dependency: medium chain esters (C8 and C10) were less efficient than short and long chain esters.

Keywords： βem>-sitosteryl fatty acid esters dipalmitoyl phosphatidylcholine Langmuir monolayer condensing

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Flow cytometric assessment of the effects of chlorine, chloramine, and UV on bacteria by using nucleic acid

Xuebiao Nie, Wenjun Liu, Mo Chen, Minmin Liu, Lu Ao

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 6, doi: 10.1007/s11783-016-0884-4

Abstract: Flow cytometry based on nucleic acid stains and CTC was established and optimized.

Keywords： Flow cytometry Escherichia coliem> Staphylococcusaureusem> UV CTC SYTO 9

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Use of dry yeast cells as a cheap nitrogen source for lactic acid production by thermophilic

Kim Yng Ooi, Jin Chuan Wu

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 3, Pages 381-385 doi: 10.1007/s11705-015-1534-2

Abstract: cells (DYC) were used as a cheap nitrogen source to replace expensive yeast extract (YE) for L-lactic acidCassava starch (200 g·L ) was converted to L-lactic acid by simultaneous saccharification and fermentationusing WCP10-4 at 50 °C in the presence of 20 g·L of DYC, giving 148.1 g·L of L-lactic acid at 27In contrast, 154.4 g·L of lactic acid was produced at 24 h with a productivity of 6.4 g·L ·h and aUse of pre-autolyzed DYC at 50 °C for overnight slightly improved the lactic acid titer (154.5 g·L )

Keywords： L-lactic acid thermophilic strain Bacillus coagulansem> dry yeast cells autolysis fermentation

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Serum Nem>-Glycan Markers for Diagnosing Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis Article

Lin Wang, Yiqi Liu, Qixin Gu, Chi Zhang, Lei Xu, Lei Wang, Cuiying Chen, Xueen Liu, Hong Zhao, Hui Zhuang

Engineering 2023, Volume 26, Issue 7, Pages 151-158 doi: 10.1016/j.eng.2023.03.008

Abstract:

The aim of this study was to explore the role of serum Nem>-glycomic-derived models in diagnosingSerum Nem>-glycan profiles were tested using DNA sequencer-assisted fluorophore-assisted carbohydrateA total of nine Nem>-glycan peaks were identified in serum samples for each subject.In distinguishing significant liver fibrosis, the diagnostic efficiency of the serum Nem>-glycanIn distinguishing liver cirrhosis, the diagnostic AUROC curve of the serum Nem>-glycan RF model

Keywords： Liver fibrosis Chronic hepatitis B Serum Nem>-glycan Nem>-glycan model Alanine aminotransferase

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Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma

Frontiers of Medicine 2023, Volume 17, Issue 2, Pages 240-262 doi: 10.1007/s11684-022-0936-z

Abstract: After identifying conserved gene modules co-expressed with EGFR or PDGFRA (EM or PM), we recently proposedan EM/PM classification scheme for adult gliomas in a histological subtype- and grade-independent mannerRNA-seq samples, and clinical samples, we here demonstrate the temporal and spatial stability of the EMThe EM and PM subtypes, which progress in a subtype-specific mode, are robustly maintained in pairedWithin individual gliomas, the EM/PM subtype was preserved across regions and single cells.

Keywords： glioma progression molecular classification EM/PM subtyping intratumor heterogeneity

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Human Prostate-Specific Antigen Carries Nem>-Glycans with Ketodeoxynononic Acid Article

Wei Wang, Tao Zhang, Jan Nouta, Peter A. van Veelen, Noortje de Haan, Theo M. de Reijke, Manfred Wuhrer, Guinevere S.M. Lageveen-Kammeijer

Engineering 2023, Volume 26, Issue 7, Pages 119-131 doi: 10.1016/j.eng.2023.02.009

Abstract:

Ketodeoxynononic acid (Kdn) is a rather uncommon class of sialic acid in mammals.Here, we report for the first time that Kdn is expressed on prostate-specific antigen (PSA) Nem

Keywords： Ketodeoxynononic acid Kdn Glycosylation Prostate cancer Prostate-specific antigen

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Profound Diversity of the Nem>-Glycome from Microdissected Regions of Colorectal Cancer, Stroma Article

Di Wang, Katarina Madunić , Tao Zhang, Guinevere S.M. Lageveen-Kammeijer, Manfred Wuhrer

Engineering 2023, Volume 26, Issue 7, Pages 32-43 doi: 10.1016/j.eng.2022.08.016

Abstract: While the Nem>-glycosylation of cell lines and serum has been widely examined, the analysis ofcancer-associated Nem>-glycans from tissues has been hampered by the heterogeneity of tumors andthe complexity of Nem>-glycan structures.In total, 116 Nem>-glycans were identified that showed profound differences in expression among>Nem>-glycans, as well as a decrease in bisected Nem>-glycans.

Keywords： Colorectal cancer Tumor Porous graphitized carbon liquid chromatography mass spectrometry N-glycomics Antibody response

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VITHM1 mediated green synthesis of silver nanoparticles: Mechanism and biological applications

Mani Abirami, Krishnan Kannabiran

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 4, Pages 542-551 doi: 10.1007/s11705-016-1599-6

Abstract: We present the microbial green synthesis of silver nanoparticles (NPs) by VITHM1 strain (MTCC No. 12465). The secondary metabolites in the cell free supernatant of this bacterium when incubated with 1 mmol/L AgNO , mediated the biological synthesis of AgNPs. The synthesized AgNPs were characterized by UV-visible spectrum, X-ray diffraction (XRD), atomic force microscope, scanning electron microscopy equipped with energy dispersive spectroscopy, transmission electron microscopy, FT-IR spectroscopy, dynamic light scattering and zeta potential. They were highly stable and, spherical in shape with the average size of 30?50 nm. The secondary metabolites involved in the formation of AgNPs were identified gas chromatography-mass spectrography. The 3D structure of the unit cell of the synthesized AgNPs was determined using XRD data base. The synthesized AgNPs exhibited significant antibacterial activity against tested bacterial pathogens, and did not show haemolysis on human red blood cells. This green synthesis could provide a new platform to explore and use AgNPs as antibacterial therapeutic agents.

Keywords： Streptomyces ghanaensisem> VITHM1 nanoparticles 3D structure antibacterial activity

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Enhanced disinfection of Escherichia coliem> and bacteriophage

Guiying RAO, Kristen S. BRASTAD, Qianyi ZHANG, Rebecca ROBINSON, Zhen HE, Ying LI

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 4, doi: 10.1007/s11783-016-0854-x

Abstract: A novel photocatalytic Ag-Cu-TiO nanowire membrane was fabricated. Bacteria and virus disinfection was improved by co-depositing Ag and Cu onto membrane. Synergetic photocatalytic effects and free metal ions of Ag and Cu contribute to disinfection. 7.68 log removal of and 4.02 log removal of bacteriophage MS2 were achieved. Titanium dioxide (TiO ) is a widely used photocatalyst that has been demonstrated for microorganism disinfection in drinking water. In this study, a new material with a novel structure, silver and copper loaded TiO nanowire membrane (Cu-Ag-TiO ) was prepared and evaluated for its efficiency to inactivate and bacteriophage MS2. Enhanced photo-activated bactericidal and virucidal activities were obtained by the Cu-Ag-TiO membrane than by the TiO , Ag-TiO and Cu-TiO membranes under both dark and UV light illumination. The better performance was attributed to the synergies of enhanced membrane photoactivity by loading silver and copper on the membrane and the synergistic effect between the free silver and copper ions in water. At the end of a 30 min test of dead-end filtration under 254 nm UV irradiation, the Cu-Ag-TiO membrane was able to obtain an removal of 7.68 log and bacteriophage MS2 removal of 4.02 log, which have met the US EPA standard. The free metal ions coming off the membrane have concentrations of less than 10 ppb in the water effluent, far below the US EPA maximum contaminant level for silver and copper ions in drinking water. Therefore, the photo-activated disinfection by the Cu-Ag-TiO membrane is a viable technique for meeting drinking water treatment standards of microbiological water purifiers.

Keywords： Photo-activated disinfection Titanium dioxide Nanowire membrane Silver Copper

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Removable Dyes—The Missing Link for In-Depth Nem>-Glycan Analysis via Multi-Method Approaches Article

Samanta Cajic, René Hennig, Valerian Grote, Udo Reichl, Erdmann Rapp

Engineering 2023, Volume 26, Issue 7, Pages 132-150 doi: https://doi.org/10.1016/j.eng.2023.02.016

Abstract: Through the detailed structural analysis of selected, dauntingly complex Nem>-glycans from chickenMoreover, this approach "visualizes" Nem>-glycans that have been difficult to identify

Keywords： Glycoproteins N-glycans Reversible labeling Hydrophilic interaction liquid chromatography Capillary gel electrophoresis Mass spectrometry

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Novel Insight into the Etiology of Haff Disease by Mapping the Nem>-Glycome with Orthogonal Mass Article

Si Liu, Yuanyuan Liu, Jiajing Lin, Bi-Feng Liu, Zhenyu He, Xiaomin Wu, Xin Liu

Engineering 2023, Volume 26, Issue 7, Pages 63-73 doi: 10.1016/j.eng.2022.09.012

Abstract: Profiling of the Nem>-glycome in HD would assist in deciphering the underlying molecular mechanismNem>-glycome profiles of both serum and serum-derived immunoglobulin G (IgG) in HD were characterized

Keywords： Haff disease Serum Immunoglobulin G Glycosylation Disease pathogenesis

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Abiotic association of phthalic acid esters with humic acid of a sludge landfill

Xiaoli CHAI, Yongxia HAO, Xin ZHAO, Guixiang LIU, Ying ZHU, Rong JI, Jun WU, Huanhuan TONG, Youcai ZHAO

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 6, Pages 778-783 doi: 10.1007/s11783-012-0434-7

Abstract: The abiotic association between phthalic acid esters (PAEs) and humic substances (HS) in sludge landfillthe abiotic association of two abundant PAEs (diethyl phthalate and di- -butyl phthalate) with humic acid

Keywords： abiotic association phthalic acid esters (PAEs) humic acid sludge landfill

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Isolation and application of predatory

Ran Yu, Shiwen Zhang, Zhoukai Chen, Chuanyang Li

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 1, doi: 10.1007/s11783-017-0900-3

Abstract: Indigenous predatory BALO strains were successfully isolated from activated sludge. Sludge SRF and CST were significantly reduced by BALOs induced biolysis process. The increase of BALO input dosage promoted the sludge biolysis efficiency. Sludge biolysis disintegrated flocs and lysed cells for internal water release. The optimal sludge biolysis time was 24 h and no pH adjustment was needed. -and-like organisms (BALOs) are a group of ubiquitous and obligate predatory bacteria and commonly used as biocontrol agents. In this study, an efficient, environmental-friendly, and convenient BALOs encouraged municipal waste sludge biolysis pretreatment technique was developed and investigated for dewaterability enhancement of excess waste sludge. The indigenous predatory BALOs were successfully isolated from the sludge for biolysis treatment. Without any chemical addition or pH adjustment, the sludge specific resistance (SRF) and capillary suction time (CST) were significantly reduced by as high as 53.4% and 23.8%, respectively within 24 h’s treatment, which would further be lowered with the increase of BALOs input dosage. However, the continuous extension of reaction time would worsen the sludge dewaterability. The decreases of SRF and CST accompanied with the increases of sludge disintegration degree and soluble chemical oxygen demand, nitrogen, and phosphorus concentrations all emphasized the contributions of BALOs’ predation activities to sludge disturbance, cell lysis, and consequently the release of sludge intracellular water to finally effectively improve the sludge dewaterability and disposal efficiency.

Keywords： Bdellovibrioem>-and-like organisms (BALOs) Biolysis Activated sludge Dewaterability Predation

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High-Throughput Profiling of Serological Immunoglobulin G Nem>-Glycome as a Noninvasive Biomarker Article

Pengcheng Liu, Xiaobing Wang, Aishe Dun, Yutong Li, Houqiang Li, Lu Wang, Yichun Zhang, Cancan Li, Jinxia Zhang, Xiaoyu Zhang, Lixing Ma, Haifeng Hou

Engineering 2023, Volume 26, Issue 7, Pages 44-53 doi: 10.1016/j.eng.2023.02.008

Abstract: ultra-performance liquid chromatography (HILIC-UPLC) was employed to analyze the composition of the plasma IgG Nem>-glycome.In addition, the composition of IgG Nem>-glycans was correlated with that of inflammatory cytokines(rem> = 0.556).

Keywords： Gastrointestinal cancer Glycosylation Immunoglobulin G Diagnostic biomarker

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Mercury enrichment in

Chunhao Dai, Pufeng Qin, Zhangwei Wang, Jian Chen, Xianshan Zhang, Si Luo

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 1, doi: 10.1007/s11783-017-0892-z

Abstract: Mercury enrichment in response to elevated atmospheric mercury concentrations in the organs of rape ( ) was investigated. Elevated soil mercury content had significant impact on mercury accumulation in rape stems, roots, seeds and seed coats. Leaf mercury in the leaves was mostly affected by atmospheric input while the stems were mostly affected by soil concentrations. Mercury in the aboveground plant tissue mainly derived from atmospheric absorption, and atmospheric mercury absorption in leaves was higher than that in the stems. Mercury enrichment in response to elevated atmospheric mercury concentrations in the organs of rape ( ) was investigated using an open top chamber fumigation experiment and a soil mercury enriched cultivation experiment. Results indicate that the mercury concentration in leaves and stems showed a significant variation under different concentrations of mercury in atmospheric and soil experiments while the concentration of mercury in roots, seeds and seed coats showed no significant variation under different atmospheric mercury concentrations. Using the function relation established by the experiment, results for atmospheric mercury sources in rape field biomass showed that atmospheric sources accounted for at least 81.81% of mercury in rape leaves and 32.29% of mercury in the stems. Therefore, mercury in the aboveground biomass predominantly derives from the absorption of atmospheric mercury.

Keywords： Open top chamber Gaseous elemental mercury (GEM) Soil Mercury Brassica napusem>

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Title Author Date Type Operation

Mapping the structure-activity relationship of

Worawan PANPIPAT, Hasene KESKIN, Zheng GUO

Journal Article

Flow cytometric assessment of the effects of chlorine, chloramine, and UV on bacteria by using nucleic acid

Xuebiao Nie, Wenjun Liu, Mo Chen, Minmin Liu, Lu Ao

Journal Article

Use of dry yeast cells as a cheap nitrogen source for lactic acid production by thermophilic

Kim Yng Ooi, Jin Chuan Wu

Journal Article

Serum Nem>-Glycan Markers for Diagnosing Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis

Lin Wang, Yiqi Liu, Qixin Gu, Chi Zhang, Lei Xu, Lei Wang, Cuiying Chen, Xueen Liu, Hong Zhao, Hui Zhuang

Journal Article

Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma

Journal Article

Human Prostate-Specific Antigen Carries Nem>-Glycans with Ketodeoxynononic Acid

Wei Wang, Tao Zhang, Jan Nouta, Peter A. van Veelen, Noortje de Haan, Theo M. de Reijke, Manfred Wuhrer, Guinevere S.M. Lageveen-Kammeijer

Journal Article

Profound Diversity of the Nem>-Glycome from Microdissected Regions of Colorectal Cancer, Stroma

Di Wang, Katarina Madunić , Tao Zhang, Guinevere S.M. Lageveen-Kammeijer, Manfred Wuhrer

Journal Article

VITHM1 mediated green synthesis of silver nanoparticles: Mechanism and biological applications

Mani Abirami, Krishnan Kannabiran

Journal Article

Enhanced disinfection of Escherichia coliem> and bacteriophage

Guiying RAO, Kristen S. BRASTAD, Qianyi ZHANG, Rebecca ROBINSON, Zhen HE, Ying LI

Journal Article

Removable Dyes—The Missing Link for In-Depth Nem>-Glycan Analysis via Multi-Method Approaches

Samanta Cajic, René Hennig, Valerian Grote, Udo Reichl, Erdmann Rapp

Journal Article

Novel Insight into the Etiology of Haff Disease by Mapping the Nem>-Glycome with Orthogonal Mass

Si Liu, Yuanyuan Liu, Jiajing Lin, Bi-Feng Liu, Zhenyu He, Xiaomin Wu, Xin Liu

Journal Article

Abiotic association of phthalic acid esters with humic acid of a sludge landfill

Xiaoli CHAI, Yongxia HAO, Xin ZHAO, Guixiang LIU, Ying ZHU, Rong JI, Jun WU, Huanhuan TONG, Youcai ZHAO

Journal Article

Isolation and application of predatory

Ran Yu, Shiwen Zhang, Zhoukai Chen, Chuanyang Li

Journal Article

High-Throughput Profiling of Serological Immunoglobulin G Nem>-Glycome as a Noninvasive Biomarker

Pengcheng Liu, Xiaobing Wang, Aishe Dun, Yutong Li, Houqiang Li, Lu Wang, Yichun Zhang, Cancan Li, Jinxia Zhang, Xiaoyu Zhang, Lixing Ma, Haifeng Hou

Journal Article

Mercury enrichment in

Chunhao Dai, Pufeng Qin, Zhangwei Wang, Jian Chen, Xianshan Zhang, Si Luo

Journal Article

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